We are developing the capability to “look inside” human arteries and describe blood flow dynamics – without getting inside. We use a combination of noninvasive imaging, such as magnetic resonance imaging, and mathematics to model blood flow in arteries of individual subjects. This allows us to obtain a tremendous amount of information about disease detection, development and treatment in an individual patient.
We also work with vascular biologists to examine how fluid dynamic shear stresses influence endothelial cell function. This helps us understand the causes of arterial disease so that prevention and treatment can be improved.